Introduction
Open‑source FHIR servers let developers spin up standards‑compliant APIs without vendor lock‑in. They’re ideal for prototypes, research projects, and even production workloads when configured correctly. Below we compare the most popular options and how to choose the right one.
Why Choose an Open‑Source FHIR Server?
- Cost: No licensing fees.
- Flexibility: Customize the codebase to fit local requirements.
- Community: Benefit from collective testing, bug fixes, and extensions.
- Transparency: Inspect code for security and compliance audits.
Evaluation Criteria
| Criterion | What to Look For |
|---|---|
| FHIR Version Support | R4, R4B, R5? |
| Performance | Bulk import/export, search indexing |
| Extensibility | Plugins, custom operations, interceptors |
| Deployment | Docker images, Kubernetes Helm charts |
| Community & Docs | Active GitHub issues, Slack/Discord, tutorials |
| License | Apache‑2.0, MIT, EPL‑2.0, etc. |
Leading Open‑Source FHIR Servers
1. HAPI FHIR JPA Server (Java)
- GitHub Stars: ~1.7k
- FHIR Versions: DSTU2 → R5
- Highlights: Mature, supports JPA/Hibernate back‑end, built‑in subscriptions, CLI tools, Docker images.
- Ideal For: Java shops, rapid prototyping, research.
2. IBM FHIR Server (Java)
- GitHub Stars: ~500
- FHIR Versions: R4, R4B
- Highlights: Focus on scalability, bulk data ($export), multi‑tenant architecture, PostgreSQL/CouchDB persistence.
- Ideal For: Enterprise deployments needing multi‑tenant isolation.
3. Microsoft OSS FHIR Server for Azure (.NET)
- GitHub Stars: ~1.4k
- FHIR Versions: R4
- Highlights: Azure Cosmos DB persistence, RBAC, SMART on FHIR auth, Docker compose, Terraform modules.
- Ideal For: Teams already on Azure wanting managed PaaS.
4. Firely Server (formerly Vonk) (.NET)
- GitHub Stars: ~300
- FHIR Versions: R4, R4B
- Highlights: Built‑in terminology service, profile validation, plugin architecture.
- Ideal For: .NET developers needing strong validation features.
5. FHIRWorks on AWS (TypeScript/Node.js)
- GitHub Stars: ~400
- FHIR Versions: R4
- Highlights: Serverless architecture (API Gateway + Lambda + DynamoDB), Cognito auth, IaC with CDK.
- Ideal For: Cloud‑native teams on AWS.
Feature Comparison (Quick Glance)
| Server | Language | DB Options | Bulk $export | Terminology | License |
|---|---|---|---|---|---|
| HAPI FHIR | Java | PostgreSQL, MySQL | ✔︎ | External | Apache‑2.0 |
| IBM FHIR | Java | PostgreSQL, CouchDB | ✔︎ | External | Apache‑2.0 |
| Azure OSS | C# | Cosmos DB | ✔︎ | External | MIT |
| Firely | C# | SQL, Mongo | ✔︎ | Built‑in | AGPL‑3.0 |
| FHIRWorks | TS | DynamoDB | ✔︎ | External | Apache‑2.0 |
Deployment Tips
- Start with Docker: All listed servers provide official images for quick trials.
- Use Infrastructure as Code: Helm charts, Terraform, or CDK accelerate repeatable deployments.
- Benchmark Early: Load‑test with Synthea‑generated data to size your cluster.
- Secure the Perimeter: Enable OAuth2/SMART scopes and enforce TLS.
Choosing the Right Server
- Language & Skillset: Align with your team’s expertise.
- Cloud Strategy: Pick a server that integrates smoothly with your preferred cloud.
- Compliance Needs: Ensure audit logging and access controls meet HIPAA/GDPR.
- Roadmap Fit: Check community activity and release cadence for future FHIR versions.
Conclusion
Open‑source FHIR servers have matured rapidly, giving healthcare innovators a robust foundation for interoperable APIs. Evaluate them against your technical stack and compliance requirements, then contribute back to keep the ecosystem thriving!
Have experience with any of these servers? Share your thoughts in the comments!

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